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Zyphra

Palo Alto, CAFounded 2021

Zyphra is an AI company combining an open-intelligence research lab with Zyphra Cloud, a full-stack AI platform for developers, enterprises, and frontier-scale organizations. It develops multimodal open models and infrastructure focused on long-term memory, continual learning, silicon performance, and long-horizon AI agents.

Founded
2021
Employees
51–100

reccy insights

Recent highlights

Zyphra expanded from model research into commercial infrastructure during 2026. On May 4, 2026, it launched Zyphra Cloud and Zyphra Inference in partnership with AMD and TensorWave, using AMD Instinct MI355X GPUs and TensorWave’s AI and high-performance computing infrastructure. On May 11, 2026, the company announced access to 15 megawatts of AMD GPU capacity through Zyphra Cloud. Its model releases have continued across multiple modalities: ZUNA, a 380M-parameter brain-computer-interface foundation model for EEG data, launched on Feb 18, 2026, while the ZAYA1-8B reasoning model was released on May 6, 2026. Zyphra also demonstrated large-scale training on an AMD and IBM Cloud cluster on Nov 24, 2025. Operationally, the company moved from Palo Alto to a full-floor office in San Francisco’s Salesforce Tower on Mar 23, 2026. Reports dated May 19, 2026 described a potential $500 million Series B at a valuation of at least $5 billion, but that financing is not reflected in the confirmed funding records.

Written by reccy's AI from company sites, press and funding records · updated Oct 2026

What makes Zyphra distinct

  1. 01Combines open-model research with a production-focused AI cloud platform.
  2. 02Focuses on open intelligence designed to give organizations control over models, data, deployments, and hardware.
  3. 03Develops AI systems for long-term memory, continual learning, and long-horizon agents.
  4. 04Builds its cloud platform on AMD infrastructure for scalable AI workloads.
  5. 05Promotes transparent, sovereign, customizable, and distributed AI deployment.

Technology & products6

  • Zyphra Cloud

    A full-stack AI platform for deploying and developing open AI systems, including model inference, agent environments, orchestration, distributed training, simulation, and dedicated compute capacity.

  • MAIA

    A multimodal AI agent for teams that coordinates shared knowledge, communication, and task execution across connected tools and workflows.

  • Zyphra Foundation Models

    A portfolio of open foundation models for language, reasoning, vision-language, audio generation, and brain-computer-interface applications.

Recent updates6

  • May 4, 2026Product launch

    Zyphra launched Zyphra Cloud, a full-stack AI platform powered by AMD Instinct MI355X GPUs on TensorWave infrastructure, along with Zyphra Inference, a serverless inference service for frontier open-weight models.

    prnewswire.com
  • May 4, 2026Partnership

    Zyphra partnered with AMD and TensorWave to power the newly launched Zyphra Cloud and Zyphra Inference platform on AMD Instinct MI355X GPUs running on TensorWave’s AI and HPC cloud infrastructure.

    prnewswire.com
  • Feb 18, 2026Product launch

    Zyphra released ZUNA, an open-source 380M-parameter diffusion autoencoder foundation model that enhances EEG data quality and supports future thought-to-text brain-computer-interface applications.

    prnewswire.com

In the Cortex

About Zyphra

Products
Zyphra Cloud, MAIA, Zyphra Foundation Models, ZAYA, ZONOS, ZUNA
Leadership
Krithik Puthalath, Founder & CEODanny Martinelli, Co-FounderMei Z., Investor
Focus areas
Unicorn
Headquarters
Palo Alto, CA
Founded
2021
Employees
51–100